Tralee making their first appearance have been handed the toughest draw of all away to last year's beaten finalists City of Armagh.
Cashel play Monivea the side that beat them 6-0 in last season's quarter final.
Clonmel are away to Skerries and will hope to do better than last season when they lost at home to Sligo 11-0.
Crosshaven travel to Dundalk and will face a difficult test against the Leinster side.
The draw for the opening rounds were made at the Aviva Stadium by IRFU President, Caleb Powell and Chairman of the Domestic Game Committee, Stephen Hilditch.
The All Ireland Junior Cup has proved extremely popular with clubs and supporters, attracting big crowds to all the games and fostering ties between Junior clubs in all four provinces.
There are four clubs from each province with the teams from Connacht, Leinster and Ulster qualifying through their position in last season's qualifying league while the Munster clubs are drawn from the four semi finalists in this season's Junior Clubs Challenge Cup.
In the first round no teams from the same province can be drawn against each other.
All Ireland Junior Cup, 2010/11, 1st Round Draw (All matches to be played on Saturday, October 30th)
A. Skerries V Clonmel
B. Armagh V Tralee
C. Cooke V Corrib
D. Tullamore V Sligo
E. Monivea V Cashel
F. Dromore V Ballina
G. Ballymoney V Boyne
H. Dundalk V Crosshaven
All Ireland Junior Cup, Quarter Final Draw (All matches to be played Saturday, November 27th)
I. Monivea/Cashel v Ballymoney/Boyne
J. Dromore / Ballina v Dundalk / Crosshaven
K. Cooke/Corrib v Skerries/Clonmel
L. Tullmore/Sligo v Armagh / Tralee
Semi Final - Saturday, February 12th, 2011
Final - April 9th/10th 2011
All Ireland Junior Cup Champions
09/10 - City of Derry
08/09 - Tullamore
07/08 - Navan
06/07 - Seapoint
05/06 - Rainey Old Boys