Derby clashes are never the ideal occasion to get things back on track and the Sportsground is one of the hardest places for Irish sides to visit as Munster will find out once again this evening.
Munster travel with a much changed side from the one that disappointed against Ospreys last time out and they give a first start to Paddy Butler at number eight and pair Ian Nagle and Donnacha Ryan in the second row while Kiwi Peter Borlase is in at thight head prop where he will come under a fair degree of scrutiny after Munster's tribulations in that area in Swansea.
Paul Warwick, who departs at the end of the season is at full back with old reliables Ronan O'Gara and Peter Stringer at half back.
Munster are four points clear at the top of the table with the chasing pack, Cardiff Blues excepted, playing each other which makes this an even more crucial game if Munster are to keep some daylight between themselves and the rest.
Given the composition of the Munster side, plus the fact that this is probably one of the games Eric Elwood has targetted, the bookies have Connacht's favourite and it will need a special effort if the Ronan O'Gara led Munster side are to upset the odds.
Connacht: I Keatley; D Fanning, N Ta'auso, K Matthews, F Carr; M Nikora, C Willis; R Sweeney, S Cronin, J Hagan; M Swift, M McCarthy; A Browne, E Taylor, J O'Connor. Replacements: A Flavin, B Fa'amausili, D Rogers, B Upton, M McComish, F Murphy.
Munster: P Warwick; B Murphy, T Gleeson, L Mafi, D Hurley; R O'Gara, P Stringer; W du Preez, M Sherry, P Borlase; D Ryan, I Nagle; A Quinlan, N Ronan, P Butler. Replacements: S Henry, Dave Ryan, J Hayes; B Holland, T O'Donnell, C Murray, J Murphy, S Deasy.
Referee: David Wilkinson (IRFU)