It had been Alan Gaffney's intention to rest Cullen, but a family illness disrupted Payne's preparation and Cullen takes over at 5. Happily, the illness has proved to be not as serious as first thought.
Meanwhile, Scott Lawson will reach a notable milestone in his rugby life when the 23-year-old hooker plays his fiftieth game for the professional team.
Munster: Christian Cullen; John Kelly, James Storey, Jason Holland, Anthony Horgan; Paul Burke, Eoin Reddan; Marcus Horan, Frank Sheahan, Gordon McIlwham; Trevor Hogan, Donncha O Callaghan; Alan Quinlan, Denis Leamy, David Wallace. Replacements: Eugene McGovern, Jerry Flannery, Tom Bowman, Jim Williams, Mike Prendergast, Rob Henderson, Paul Devlin.
Glasgow: Colin Shaw; Rory Lamont, Graeme Morrison, Scott Barrow, Kenny Logan; Calvin Howarth, Graeme Beveridge; Kevin Tkachuk, Scott Lawson, Andrew Kelly; Joe Beardshaw, Dan Turner; Steve Swindall, Cammy Mather (capt) Paul Dearlove. Replacements: Fergus Thomson, Ben Prescott, Andrew Hall, John Barclay, Alasdhair McFarlane, Andrew Henderson, Gareth Maclure.
Referee - Jonathan Kaplan.