Ronan O'Gara returns to the side as does Peter Stringer and Denis Leamy, who will captain the side while Mick O'Driscoll who led the Munster revival when introduced at the Stadio Monigo partners Donnacha Ryan in the second-row and Coughlan and O'Donnell rightly retain their places in the backrow having impressed against Treviso.
Meanwhile Edinburgh who named their side yesterday, travel with a strong outfit that includes the Magners current leading try scorer Tim Visser and current Scotland squad members lock Scott MacLeod and number 8 Ross Rennie.
Tickets for the game are still available from the ticket office in Thomond Park Stadium, the Munster Rugby offices Tramore Road in Cork, from the Munster Rugby Stores in O'Connell St Limerick and Maylor St. Cork, from Ticketmaster outlets nationwide and online here.
Tickets for the game will be available to purchase at Thomond Park Stadium on the night.
Munster: J Murphy, D Howlett, L Mafi, P Warwick, D Hurley, R O'Gara, P Stringer, W du Preez, D Varley, T Buckley, D Ryan, M O'Driscoll, D Leamy capt, T O'Donnell, J Coughlan. Replacements: D Fogarty, M Horan, S Archer, I Nagle, B Holland, D Williams, T Gleeson, S Zebo.
Edinburgh: C Paterson, L Jones, B Cairns, J King, T Visser, D Blair, G Laidlaw capt, K Traynor, A Kelly, G Cross, S MacLeod, S Turnbull, F McKenzie, N Tatel, R Rennie. Replacements: A Walker, L Niven, D Young, A MacDonald, R Grant, N de Luca, S Webster, J Thompson.
Referee: Nigel Owens.