Elsewhere in the forwards, Penney has named a completely different front-row as Dave Kilcoyne, Damien Varley and BJ Botha start with Dave Foley and Dave O'Callaghan also coming into the side. Both Foley and O'Callaghan have most recently been invovled in Munster's British and Irish Cup campaign. Varley captains the side for the second time this season.
In the backs, exciting winger Ronan O'Mahony keeps his place and starts in his first competitive game at Thomond Park.
Ian Keatley comes back in at out-half ahead of last week's man of the match JJ Hanrahan who moves to the replacements.
Duncan Williams starts at scrum-half and Felix Jones returns at full-back after a slight ankle sprain ruled him out of action last weekend, with Johne Murphy moving to the right wing in place of Andrew Conway who is suffering from bruised ribs.
The centre partnership of Ivan Dineen and Casey Laulala remains intact.
Corkman Duncan Casey takes his place on the bench and the hooker will be hopeful of making his first league appearance for Munster.
James Downey was not considered due to a back spasm.
Munster: Felix Jones; Johne Murphy, Casey Laulala, Ivan Dineen, Ronan O'Mahony; Ian Keatley, Duncan Williams; Dave Kilcoyne, Damien Varley Capt., BJ Botha; Donncha O'Callaghan, Dave Foley; Dave O'Callaghan, Sean Dougall, CJ Stander. Replacements: Duncan Casey, James Cronin, John Ryan, Billy Holland, James Coughlan, Cathal Sheridan, JJ Hanrahan, Cian Bohane.
Tickets are on sale for this game online here, from the Munster Rugby Ticket offices in Musgrave Park and Thomond Park or by calling Ticketmaster on 0818 719300.
The mobile ticket office at Hassett's Cross will be open until 7pm today, and the ticket office will be open from 9am on match-day.
Family packs are available for €40 for 2 Adults and 2 Juniors.
Junior - Under 16 years of age