Paul Warwick, who departs at the end of the season is at full back with old reliables Ronan O'Gara and Peter Stringer at half back.
Munster are four points clear at the top of the table with the chasing pack, Cardiff Blues excepted, playing each other which makes this an even more crucial game if Munster are to keep some daylight between themselves and the rest.
Given the composition of the Munster side, plus the fact that this is probably one of the games Eric Elwood has targetted, the bookies have Connacht's favourite and it will need a special effort if the Ronan O'Gara led Munster side are to upset the odds.
Connacht: I Keatley; D Fanning, N Ta'auso, K Matthews, F Carr; M Nikora, C Willis; R Sweeney, S Cronin, J Hagan; M Swift, M McCarthy; A Browne, E Taylor, J O'Connor. Replacements: A Flavin, B Fa'amausili, D Rogers, B Upton, M McComish, F Murphy.
Munster: P Warwick; B Murphy, T Gleeson, L Mafi, D Hurley; R O'Gara, P Stringer; W du Preez, M Sherry, P Borlase; D Ryan, I Nagle; A Quinlan, N Ronan, P Butler. Replacements: S Henry, Dave Ryan, J Hayes; B Holland, T O'Donnell, C Murray, J Murphy, S Deasy.
Referee: David Wilkinson (IRFU)