Damien Varley returns from his bout off illness to start in the front row with Dave Kilcoyne and Stephen Archer.
Tommy O'Donnell joins O'Connell and O'Mahony in returning to the pack, while there is a change in half-backs this week with Cathal Sheridan and Ian Keatley starting.
The backline sees Felix Jones at fullback with Andrew Conway, Ivan Dineen and Casey Laualala joining Ronan O'Mahony.
Keith Earls misses out this week with a bruised shoulder and there is no place for JJ Hanrahan in the squad due to a tight groin but both are expected to train next week.
James Cronin received the all clear from the scan of his lower back but will not be involved this weekend.
Munster: Felix Jones; Andrew Conway, Casey Laulala, Ivan Dineen, Ronan O'Mahony; Ian Keatley, Cathal Sheridan; Dave Kilcoyne, Damien Varley, Stephen Archer; Donncha O'Callaghan, Paul O'Connell; Peter O'Mahony Capt., Tommy O'Donnell, James Coughlan. Replacements: Duncan Casey, John Ryan, BJ Botha, Dave Foley, CJ Stander, Duncan Williams, Johnny Holland, Johne Murphy.