Glenn Delaney has named a young side for this fixture, due to a heavy league schedule.
Dual-registered Matt Everard, 19, comes into the starting line-up after sitting on the bench against Bristol on Sunday while Dave Marshall comes in at fly half.
Greig Tonks moves to inside centre for the match up and Dan Hemingway returns to the side.
Peter Cook, Greg Sammons, Ben Buxton, Ian Nimmo, Nic Carter, Jonny Baird, Matt Everard, Dan Hemingway; Dan White, Dave Marshall, Donald Blake, Greig Tonks, Tim Streather, Jack Cobden, Andy Savage.
Neil Fowkes, Tom Youngs, Petrus Du Plessis, Nic Rouse, Phil Eggleshaw, Will Nelson, Jamie Barnard.