Hooker Matthew Crockett is also unavailable due to injury, so Kevin Corrigan will start with Damien Varley coming into the squad.
"The loss of David and Matt is unfortunate, and disappointing particularly for the players themselves. "said coach Mick Galwey. " But we have two excellent replacements in Fank Cogan and Kevin Corrigan and I would have no worry about their ability to perform, as both came on during the last game and played very well".
Speaking of the 20-17 win over England Counties Galwey continued,"We were delighted with the team's performance last time out. They gelled together very quickly and really put it up to a physically bigger England side. But this game is an even bigger challenge and we will have to repeat that sort of performance if we want to be in with a chance of beating the Scots on Friday.
"Overall the experience has been fantastic for the management and the players, so we want to end the season on a high note".
(AIB Club International Select v Scotland on Friday, 9th March, Boroughmuir RFC, Meggetland. KO 7pm)
Richard McCarter (Dungannon); Niall O'Brien (Clontarf), Kevin Hartigan (Garryowen), Glen Telford (Dungannon), Cronan Healy (Cork Constitution), Andrew Thompson (Shannon), Fiach O'Loughlin (Clontarf); Dan O'Connell (Galwegians), Kevin Corrigan (Lansdowne), Simon Shawe (Ballymena); Merle O'Connell (Cork Constitution), Alan Maher (Lansdowne); Peter Malone (Garryowen) Captain, Conor Hartigan (Buccaneers), Frank Cogan (Cork Constitution)
Replacements: Damien Varley (Garryowen), Stephen Nolan (Terenure College), Simon Crawford (Clontarf), Oisin Hennessy (Dungannon), Mark Bruce (Buccaneers), Barry Keeshan (Dolphin), Andrew Finn (Shannon)
Ireland (Women) v Scotland, Saturday March 10, (11am), Meggetland, Edinburgh
Ireland: Sarahjane Belton (UL Bohemian) capt; Jeannette Feighery (UL Bohemian), Lynne Cantwell (Richmond), Shannon Houston (Blackrock), Grace Davitt (Blackrock); Jo O'Sullivan (Richmond), Louise Beamish (UL Bohemian); Fiona Coghlan, (UL Bohemian), Jess Limbert (Cooke), Marie Barrett (Highfield); Caroline Mahon (UL Bohemian), Germaine Healy (Rathdrum); Eimear O'Sullivan (Clonakilty), Sinead Ryan (Navan), Orla Brennan (Blackrock).
Replacements: Yvonne Nolan (Blackrock), Laura Guest (Clonakilty), Debbie Clarke (Blackrock), Rachel Boyd (Cooke), Nicole Fitzgerald (UL Bohemian), Mairead Kelly (UL Bohemian), Amanda Greensmith (Shannon)