Elsewhere, there is a second start for Brian Carney following on from his try-scoring debut against Ulster and Under 21 international Keith Earls is named among the replacements.
Ospreys lie in third place in the table eight points off the leaders Leinster but with a game in hand and a game in the Liberty Stadium against Leinster at the end of the month. So Munster's return to Wales a week after exiting the Heineken Cup will be a difficult assignment, a point recognised by Kidney.
"Of course it's been a tough week. Always is when you go out of a competition. But what we have to do now is lift ourselves for the next challenge. This is when we find out about ourselves.
"We have to park that (Heineken Cup defeat) now. There will an opportunity to revisit it and see what we need to correct.
"We can't do anything in the short term now about what happened last weekend but we do have control over what happens on Saturday and that's what we must focus on".
Munster: M Lawlor, B Carney, B Murphy, L Mafi, A Horgan; J Manning, T O'Leary; F Pucciariello, F Sheahan, T Buckley; D O'Callaghan, D Ryan; A Quinlan, J O'Sullivan, A Foley capt. Replacements: J Flannery, M Horan/Eugene McGovern, S O'Connor, J Coughlan, B O'Meara, R O'Gara, K Earls.