Bruff remain rooted to the foot of Division 2A and they travel to Killiney to take on fellow strugglers Seapoint and must win to keep their hopes alive of avoiding the drop.
In Division 1 of the Munster Junior League leaders Kanturk can take another step closer to the title as they will be looking to claim maximum points from their home meeting with Muskerry, who have recently been assured of top flight rugby for next season.
Second-placed St Mary's will also be seeking maximum points from their home meeting with Newcastle West, who remain in third place after collecting a losing bonus point from last week's home defeat by Tralee.
The four sides propping up the table will have their work cut out as they all have away games.
Former AIL side Waterpark make the long trip to the Kingdom to take on Tralee and 'Park are in grave danger of dropping a division with only one win in the current campaign.
Bottom side Mallow take on Old Christians at Rathcooney and Galbally are away to Clonmel.
Skibbereen travel to East Cork to take on Cobh Pirates and the only mid-table clash sees Clonakilty travelling to the Premier County to take on Kilfeacle.
In Division 2 Kinsale will be looking to take another step closer to promotion as they travel to Suirside to take on Waterford City at Kilbarry.
Struggling Killorglin will be looking to make the most of home advantage count in their bid to avoid a quick return to Division 3 as they entertain Youghal at the Kerry venue.
Killarney are at home to bottom side Newport and the Kingdom side should have little difficulty in seeing off 'Port as they recently defeated the same opposition 19-3 in the Munster Junior Clubs' Challenge Shield at the Tipperary venue.
The two sides chasing promotion form Division 3 have away ties as leaders Ballincollig play Douglas in a local derby at Moneygourney and fellow promotion chasers Abbeyfeale should have little difficulty in seeing off the challenge of bottom side Dunmanway-Bantry Bay in West Cork.
The only other game sees Fermoy locking horns with North Cork neighbours Charleville at the Showgrounds with nothing more than local pride at stake.
WEDNESDAY 5th MARCH
Seat Schools Senior Cup Semi Final: Ardscoil Ris v St. Munchin's, Grove Island, 3.00;
Limerick City Under 15 Cup: Rockwell v St. Munchin's, Rockwell, 2.30;
Limerick City Under 15 B Cup: Rockwell v St. Munchin's, Rockwell, 2.30;
CUSAI All Ireland League: C.I.T. v Carlow IT, C.I.T., 7.00;
Womens Colleges: U.C.C. v Carlow IT, Curaheen Road, 1.30;
THURSDAY 6th MARCH
SEAT Munster Schools Junior Cup Quarter Final Replay: Rockwell v Castletroy, Clanwilliam Park, 3.00;
FRIDAY 7th MARCH
Ulster Bank League Division 1A: Lansdowne v St. Mary's College, Aviva Stadium, 7.30;
Webb Cup: Kilfeacle v Shannon, Kilfeacle, 8.00;
South Junior 2 Cup: Clonmel v Waterford City, Clonmel, 7.30;
Old Christians v Clonakilty, Rathcooney, 7.15;
Seat Schools Senior Cup Semi Final: Crescent College Comp. v Castletroy College, Rosbrien, 3.00;
SATURDAY 8th MARCH
Six Nations: Ireland v Italy, Aviva Stadium, 2.30;
Ulster Bank League Division 1A: Ballynahinch v Old Belvedere, Ballymacarn Park, 2.30;
Gleeson League Section A: Old Crescent v Thomond, Rosbrien, 2.30;
St. Mary's v Galbally, Grove Island, 4.30;
Section B: Young Munster v Clanwilliam, Derryknockane, 12.30;
South Junior 2 Cup: Bandon v Kinsale, Bandon, 6.00;
Kanturk v Skibbereen, Kanturk, 3.00;
Under 20 South Western Conference Division 1: Buccaneers v Galwegians, Dubarry Park, 2.30;
Garryowen v Shannon, Dooradoyle, 12.30;
U.C.C. v Highfield, Mardyke, 12.00;
U.L. Bohemian v Cork Constitution, Annacotty, tbc;
Division 2: Midleton v Bruff, Towns Park, 1.00;
Dolphin v Nenagh Ormond, Musgrave Park, 12.30;
South Under 18 League Phase 2: Bantry Bay v Kanturk, Mahon, 11.00;
Crosshaven v Midleton, Crosshaven, 1.00;
Mallow v Skibbereen, Mallow, 12.00;
South Under 16 League Phase 2: Charleville v Mallow, Charleville, 11.00;
Highfield v Ballincollig, Woodleigh Park, tbc;
Skibbereen v Kinsale, Skibbereen, 1.00;
South Under 16 Development League: Cobh Pirates v Carrigaline, Cobh, tbc;
Kanturk v Cork Constitution, Kanturk, 12.00;
SUNDAY 9th MARCH
Ulster Bank League Division 1B: Shannon v Corinthians, Coonagh, 2.30;
Division 2A: Seapoint v Bruff, Kilbogget Park, 2.30;
Munster Junior League Division 1: Clonmel v Galbally, Clonmel, 2.30;
Cobh Pirates v Skibbereen, Cobh, 2.30;
Kanturk v Muskerry, Kanturk, 2.30;
Kilfeacle v Clonakilty, Kilfeacle, 2.30;
Old Christians v Mallow, Rathcooney, 2.30;
St. Mary's v Newcastle West, Grove Island, 2.30;
Tralee v Waterpark, Tralee, 2.30;
Division 2: Killarney v Newport, Killarney, 2.30;
Killorglin v Youghal, Killorglin, 2.30;
Waterford City v Kinsale, Waterford, 2.30;
Division 3: Douglas v Ballincollig, Moneygourney, 2.30;
Dunmanway-Bantry Bay v Abbeyfeale, Dunmanway, 2.30;
Fermoy v Charleville, Fermoy, 2.30;
Munster Seconds League North: Nenagh Ormond v U.L. Bohemian, Nenagh, 12.30;
Richmond v Old Crescent, Richmond Park, 2.30;
Munster Seconds League South: Cashel v Cork Constitution, Cashel, 2.30;
Dolphin v Highfield, Musgrave Park, 2.30;
Midleton v Sunday's Well, Towns Park, 2.30;
South Junior 2 Cup: Cobh Pirates v Mallow, Cobh, 12.00;
Iveragh v Highfield, Cahirciveen, 2.30;
Mitchelstown v Cashel, Mitchelstown, 2.30;
Muskerry v Dungarvan, Ballyanly, 2.30;
Shandon v Waterpark, Whitechurch, 2.30;
Tralee v Cork Constitution, Tralee, 2.30;
U.C.C. v Corca Dhuibhne, Curaheen Road, 2.30;
South Junior 3 League Phase 2: Ballincollig v Midleton, Tanner Park, 12.00;
Cork Constitution v Sunday's Well, Temple Hill, 12.00;
South Junior 3B League: Cork Transport v Charleville, Corn Field, 2.30;
Pan Munster Under 18 Semi Finals: Bruff v Waterpark, Kilballyowen Park, 2.00;
Young Munster v Tralee, Clifford Park, 1.00;
Pan Munster Under 16 Semi Final: Waterpark v Bantry Bay, Ballinakill, 2.00;
East Under 18 Development League: Fethard v Clonmel, Fethard, 11.00;
Thurles v Cashel, Thurles, 11.00;
East Under 16 Development League: Cashel v Nenagh Ormond, Cashel, 12.30;
Clonmel v Clanwilliam, Clonmel, 11.00;
East Under 14 Plate: Cashel v Clanwilliam, Cashel, 11.00;
East Under 13 Development League: Cashel v Clanwilliam, Cashel, 11.00;
Nenagh Ormond v Kilfeacle, Nenagh, 11.00;
Waterpark v Galbally, Ballinakill, 12.00;
South Under 16 League Phase 2: Midleton v Old Christians, Towns Park, 12.00;
South Under 14 League Semi Final: Mallow v Midleton, Mallow, 12.00;
All Ireland Womens Shield: Nenagh Ormond v Tralee, Nenagh, 2.30;
All Ireland Womens Plate: Ballincollig v Young Munster, Tanner Park, 1.00;
Women's Development League Group A: St. Senan's v Clonmel, Jim Slattery Park, 1.00;
Group B: Bruff v Youghal, Kilballyowen Park, 1.00;
Dolphin v Bandon, Musgrave Park, 1.00;
St. Mary's v Cashel, Corbally, 1.00;