Tries from Alan McMahon and Shane Fenton and two conversions and a penalty by Bill Johnston gave Munster a 17-0 interval lead.
John Poland, Willie Coffey and Calvin Nash added further tries for Munster in the second half and Johnson converted two of the tries.
Munster complete their campaign with a home game against Ulster next Saturday at Musgrave Park
Munster: Alan McMahon (Rockwell Colege); Calvin Nash (Crescent College Comp.), Paul Kiernan (Captain) (PBC), Dave O'Mahony (Ard Scoil Rís), Willie Coffey (Rockwell College); Bill Johnston (Rockwell College), John Poland (PBC); Joe Ring (PBC), Shane Fenton (Ard Scoil Rís), Greg Roche (CBC); Cian Barry (CBC), Sean O'Connor (Rockwell College); Ronan Murphy (Castletroy College), Sean Fitzgerald (Crescent College Comp.), Kelvin Browne (Ard Scoil Rís).
Replacements: Vincent O'Brien (CBC), Peter Meyer (St. Munchin's College), Shane O'Hanlon (CBC), Evan Mintern (CBC), Tommy Anglim (Rockwell College), Rory Cunningham (Castletroy College), Michael Clune (CBC), Gary O'Sullivan (Crescent College).
Connacht: Ryan Feehily (Sligo Grammar); Jack Keegan (Summerhill College Sligo), Ruairi Green (St. Pauls Oughterard), Tim Costigan (Glenstal Abbey School), Patrick Daly (Ballinrobe Community School); Charlie McMicken (Marist College Athlone), Stephen Kerins (Summerhill College Sligo); Conan O'Donnell (Summerhill College Sligo), Niall Higgins (Garbally College Ballinasloe), Conor Kenny (Garbally College Ballinasloe); Peter Claffey (Garbally College Ballinasloe), Dan Trayers (Cistercian College Roscrea); Aaron Wootton (St. Gerald's College Castlebar), Eoghan Maher (Athenry Vocational School), Matthew Cosgrove (Captain) (Sligo Grammar).
Replacements: Michael O'Connell (St. Edna's College Galway), Joe Ugbo (Yeats College Galway), Eoghan Slevin (Athlone Community College), Sam Holland (Garbally College Ballinasloe), Dylan Connolly (Garbally College Ballinasloe), Tom McHale (Rice College Westport), Sean Horan (Garbally College Ballinasloe), Paddy Griffin (Calasanctius Oranmore).