Cork Constitution's Simon Zebo and Shannon's Duncan Casey have fallen foul of Clarke's changes as both players are dropped from the 22. 

UCC's Bryan Cagney moves to the replacements making way for Jack O'Connell, as Dave O'Callaghan and Patrick Butler both hold on to their starting places. 

Shannon and Munster U20s player Gareth Quinn McDonogh gets the call up to the Irish U20s side for the first time. 

Ireland U20 team to play Wales U20:
15 - Andrew Conway (Blackrock College/Leinster)
14 - Darren Hudson (St. Mary's College/Leinster)
13 - Brendan Macken (Blackrock/Leinster)
12 - Nevin Spence (Ballynahinch/Ulster)
11 - Tiernan O'Halloran (Galwegians/Connacht)
10 - James McKinney (Queen's University/Ulster)
9 - John Cooney (UCD /Leinster)
1 - Jack O'Connell (Lansdowne/Leinster)
2 - Niall Annett (Belfast Harlequins/Ulster)
3 - Stewart Maguire (Old Belvedere/ Leinster)
4 - David O'Callaghan (UCC/Munster)
5 - Ben Marshall (UCD/Leinster)
6 - Rhys Ruddock (UCD/Leinster) (Capt.)
7 - Dominic Ryan (Lansdowne/Leinster)
8 - Patrick Butler (Shannon/Munster)

Replacements:
16 - Risteard Byrne (UCD/Leinster)
17 - Bryan Cagney (UCC/Munster)
18 - Brian Hayes (Cork Constitution/Munster)
19 - Robin O'Sullivan (Bective Rangers/Leinster)
20 - Michael Heaney (Belfast Harlequins/Ulster)
21 - Gareth Quinn McDonogh (Shannon/ Munster)
22 - Eoin Griffin (Corinthians/Connacht) 20 - Michael Heaney